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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3I
All Species:
32.73
Human Site:
S217
Identified Species:
65.45
UniProt:
Q13347
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13347
NP_003748.1
325
36502
S217
N
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
Chimpanzee
Pan troglodytes
XP_001161562
325
36425
S217
N
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535328
325
36439
S217
N
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD9
325
36442
S217
N
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
Rat
Rattus norvegicus
B0BNA7
325
36442
S217
N
T
A
K
L
F
D
S
T
S
L
E
H
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001157867
325
36471
C217
N
T
A
K
L
F
D
C
T
T
L
E
H
L
K
Frog
Xenopus laevis
Q66J51
325
36477
S217
C
T
S
K
L
F
D
S
T
S
L
E
H
Q
K
Zebra Danio
Brachydanio rerio
Q7ZV55
325
36268
S217
C
T
A
K
M
F
D
S
S
T
L
E
H
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02195
326
36141
S219
T
T
A
K
L
F
D
S
E
S
L
M
C
L
K
Honey Bee
Apis mellifera
XP_392780
326
36609
S218
N
T
A
K
L
F
D
S
E
S
L
M
L
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40217
347
38737
V225
T
N
S
F
L
V
D
V
S
T
L
Q
V
L
K
Red Bread Mold
Neurospora crassa
Q7RXH4
346
38778
A220
K
T
S
K
L
I
T
A
K
D
L
E
V
L
K
Conservation
Percent
Protein Identity:
100
77.5
N.A.
99.3
N.A.
99.3
99.3
N.A.
N.A.
94.1
89.8
83.6
N.A.
60.7
59.8
N.A.
N.A.
Protein Similarity:
100
80.3
N.A.
99.6
N.A.
100
100
N.A.
N.A.
97.5
97.2
93.5
N.A.
77.3
78.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
86.6
80
73.3
N.A.
60
66.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
86.6
N.A.
66.6
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.8
49.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.6
66.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
17
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
92
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
0
75
0
0
0
% E
% Phe:
0
0
0
9
0
84
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
92
0
0
0
0
9
0
0
0
0
0
100
% K
% Leu:
0
0
0
0
92
0
0
0
0
0
100
0
9
42
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
59
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
50
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
25
0
0
0
0
75
17
34
0
0
0
0
0
% S
% Thr:
17
92
0
0
0
0
9
0
59
59
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
9
0
0
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _